1. Start by pinning down which QuickBooks product you're actually on. That decides everything else here. QuickBooks Self-Employed (QBSE) is built for sole proprietors filing a Schedule C and has a built-in quarterly tax estimator. QuickBooks Online and Desktop, the versions most small businesses run, don't estimate income tax or self-employment tax, no matter how complete your books are.
2. On QuickBooks Self-Employed, open the Taxes tab and select Quarterly. You'll see the estimated payment for the current quarter, calculated from your categorized income, expenses, and mileage. Keep your transactions reviewed through the quarter, since the estimate is only as good as the data behind it.
3. Check the due date and pay it. QBSE shows the amount and the deadline. You can pay directly from the app once you've enrolled in e-pay through EFTPS, or take the number it gives you and pay through IRS Direct Pay or by mailing a check with the 1040-ES voucher.
4. On QuickBooks Online or Desktop, skip the estimate and go to your accountant or a 1040-ES worksheet instead. Neither product has anything resembling QBSE's Quarterly tab. The number has to come from outside QuickBooks entirely.
5. Make the payment outside QuickBooks. Pay through IRS Direct Pay, EFTPS, or mail a check, the same options available to QBSE users who haven't set up in-app e-pay.
6. Record the payment as a transaction once it's made. Enter it as a check or expense so your books reflect the cash leaving the business. Most accountants book it to an owner's draw or equity account rather than a tax expense line, since income tax on a pass-through business's profit is personal, not a deductible expense; a C corp's own tax liability works differently. Check with your accountant on which applies to you.