The Slack app posts new tickets and updates into a channel and lets agents reply from Slack directly. The Jira app links a ticket to a Jira issue so a bug report doesn't need two separate trackers. Salesforce and HubSpot both have listed apps that sync contacts and show each system's record as a sidebar in the other, similar to how Freshworks' own Freshsales pairs with Freshdesk. WordPress and a few e-commerce platforms get a support widget embedded on the site itself.
All of these cover the common case well: get basic visibility and status syncing working fast, with no developer involved. None of them are built to handle business-specific logic, like syncing a custom field, triggering a Freshdesk ticket only under certain account conditions, or pushing a resolved ticket's outcome into a specific stage of a Salesforce pipeline instead of just updating a generic status field.